課程名稱 |
生物系統模擬及計算二 SIMULATION AND COMPUTATION FOR BIOSYSTEMS(II) |
開課學期 |
99-1 |
授課對象 |
生物資源暨農學院 生物環境系統工程學研究所 |
授課教師 |
廖中明 |
課號 |
BSE8009 |
課程識別碼 |
622 D0380 |
班次 |
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學分 |
3 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期四2,3,4(9:10~12:10) |
上課地點 |
農工金城 |
備註 |
總人數上限:15人 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
Instructor: Dr. Chung-Min Liao, Department of Bioenvironmental Systems Engineering, National Taiwan University
Topics:
● Basics and Techniques for Modeling Deterministic Compartmental
Systems
● Basics and Techniques for Modeling Stochastic Compartmental
Systems
● Identifiability
● Estimation and Estimability
● Design of Experiments
● Applications
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課程目標 |
The objectives are to apply the mathematical modeling and computation tchniques to investigate the prombles of environmental systems. |
課程要求 |
Grading Policy:
1.Home Work: 30%
2.Term Paper: 30%
3.Oral presentation: 40%
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
1.Jacquez, JA. 1996. (3rd ED.) Compartmental Analysis in Biology
and Medicine. BioMedware, Ann Arbor, MI.
2.Jacquez, JA. 1999. Modeling with Compartments. BioMedware, Amm
Arbpr, MI.
3.Ekins, S. 2007. Computational Toxicology. John Wiley & Sons, New Jersey.
4.Lecture Notes. |
參考書目 |
● Journals.
1.Environmental Toxicology and Chemistry
2.Biosystems
3.Ecosystems
4.Toxicology and Applied Pharmacology
5.Ecological Modelling
6.Applied Mathematical Modelling
7.Environmental Science and Technology
8.Mathematical Biosciences |
評量方式 (僅供參考) |
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週次 |
日期 |
單元主題 |
第1週 |
9/16 |
Compartmental Systems |
第2週 |
9/23 |
Linear Compartmental Systems with Constant Coefficients |
第3週 |
9/30 |
Linear Compartmental Systems with Periodic Coefficients |
第4週 |
10/07 |
System with Time Lag |
第5週 |
10/14 |
Modeling and Modeling Systems |
第6週 |
10/21 |
Compartmental Systems with Linear Rate Law |
第7週 |
10/28 |
Nonlinear Law in Basically Deterministic Compartmental Systems |
第8週 |
11/04 |
Model Applications |
第9週 |
11/11 |
Oral Presention (I) |
第10週 |
11/18 |
An Introduction to Toxicology and Its Methodologies |
第11週 |
11/25 |
Physiologically Based Pharmacokinetic and Pharmacodynamic Modeling |
第12週 |
12/02 |
Systems Toxicology |
第13週 |
12/09 |
Computational Approaches for Assessment of Toxicity |
第14週 |
12/16 |
Application of Interpretable Models to ADME/TOX Problems |
第15週 |
12/23 |
Application in Aquatic Toxicology |
第16週 |
12/30 |
Environmental and Ecological Toxicology: Computational Risk Assessment |
第17週 |
1/06 |
Oral presention (II) |
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